Nephrogenic diabetes insipidus is not same with diabetes mellitus. We know that diabetes mellitus is some conditions of the body whereas it has high blood pressure or high blood glucose level. Beside that commonly the diabetes sufferers also have high cholesterol and they have big risk of diabetes complications.
Diabetes insipidus is kind of serious healthy problem that attack the kidneys. This disease caused by the kidneys can not respond the anti diuretic hormone (ADH) to regulate fluid balance.
Finally the patients of this disease will pass urine more than usual and always feel thirsty. The other types of the diabetes insipidus are central diabetes insipidus. This disease caused by the brain can not produce enough ADH.
In diabetes insipidus patients, a part or whole kidneys are not functioning properly. Kidneys can not respond to the hormone ADH so the kidneys can not properly absorb the water. And the patients will feel passing urine more than usual.
The Signs of Nephrogenic Diabetes Insipidus
When the kidneys loss its function to absorb the water, so the patient will feel some symptoms of this disease. They will feel so thirsty every time and has excessive urine production. In some cases the symptoms of this disease could be more extreme, they will have much more fluid loss and causes dehydration.
Dehydration is kind of bad condition where the body has electrolyte imbalances. This is really bad condition and must get medical check up as soon as possible. If the patients feel unexplained weakness, muscle pains, and irritability, they should get treatment quickly because of they have felt the symptoms of electrolyte imbalances. If they not quickly get the treatment, it will be so dangerous for them.
The Kinds of Nephrogenic Diabetes Insipidus
The cause of this disease in general there are two kinds. In patients who are suffering this disease since infancy, most likely this is a disease that is inherited from parents. Then finally the kidneys can not function properly to respond to the hormone ADH, resulting in uncontrolled urine excretion. And then in adult patients, it usually happens because the effects of drugs or electrolyte abnormalities.
For more detail, the cause of this disease in adult are they have high calcium level in the blood, low potassium level in the blood, and they has dysfunction kidneys. Drugs like lithium, demeclocycline, ofloxacin, and orlistat are the most effecting in this nephrogenic diabetes insipidus.